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MAB5460

Sigma-Aldrich

Anti-Nkx2.1 Antibody, clone 8G7-G3-1

ascites fluid, clone 8G7-G3-1, Chemicon®

Sinonimo/i:

TTF-1, Thyroid Transcription Factor-1

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

ascites fluid

Tipo di anticorpo

primary antibodies

Clone

8G7-G3-1, monoclonal

Reattività contro le specie

human

Confezionamento

antibody small pack of 25 μL

Produttore/marchio commerciale

Chemicon®

tecniche

immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotipo

IgG1

N° accesso NCBI

NM_001079668.1
NM_003317.3

N° accesso UniProt

P43699

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... NKX2-1(7080)

Specificità

Nkx2.1 (Thyroid Transcription Factor-1, TTF-1).

Immunogeno

Recombinant rat Nkx2.1.

Applicazioni

This Anti-Nkx2.1 Antibody is validated for use in WB, IH(P) for the detection of Nkx2.1.
Western blot. The antibody reacts with a 40 kDa band in immunoblots of nuclear extracts or whole cell lysates from the Nkx2.1 positive cell lines MLE15, H441-4, H345 and rat type II pmeumocyte cells.

Immunohistochemistry. The antibody can be used on formalin-fixed paraffin embedded tissue. Heat induced epitope retrieval is recommended.

Optimal working dilutions must be determined by end user.

Qualità

Tested

Altre note

Please refer to lot specific datasheet.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Weronika Szadzinska et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(44), 9129-9140 (2021-09-15)
In contrast to easily formed fear memories, fear extinction requires prolonged training. The prelimbic cortex (PL), which integrates signals from brain structures involved in fear conditioning and extinction such as the ventral hippocampus (vHIP) and the basolateral amygdala (BL), is
Yan Liu et al.
Nature biotechnology, 31(5), 440-447 (2013-04-23)
Dysfunction of basal forebrain cholinergic neurons (BFCNs) and γ-aminobutyric acid (GABA) interneurons, derived from medial ganglionic eminence (MGE), is implicated in disorders of learning and memory. Here we present a method for differentiating human embryonic stem cells (hESCs) to a
Xinyu Chen et al.
PLoS biology, 20(11), e3001868-e3001868 (2022-11-18)
The striatum links neuronal circuits in the human brain, and its malfunction causes neuronal disorders such as Huntington's disease (HD). A human striatum model that recapitulates fetal striatal development is vital to decoding the pathogenesis of striatum-related neurological disorders and
Saaket Varma et al.
American journal of physiology. Lung cellular and molecular physiology, 306(5), L405-L419 (2014-01-01)
Chronic injury of alveolar lung epithelium leads to epithelial disintegrity in idiopathic pulmonary fibrosis (IPF). We had reported earlier that Grhl2, a transcriptional factor, maintains alveolar epithelial cell integrity by directly regulating components of adherens and tight junctions and thus
Zhenyu Chen et al.
Stem cell reports, 11(5), 1257-1271 (2018-11-20)
It is highly desirable to specify human developmental principles in an appropriate human model with advanced genetic tools. However, genetically engineering human cells with lineage-tracing systems has not been achieved. Here we introduce strategies to construct lineage-tracing systems in human
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