8.08610

2,2,2-Trichloroethanol

for synthesis

• Sinonimo/i: 2,2,2-Trichloroethanol, ß,ß,ß-Trichloroethyl alcohol
• Formula empirica (notazione di Hill): C₂H₃Cl₃O
• Numero CAS: 115-20-8
• Peso molecolare: 149.40
• Numero MDL: MFCD00004677
• Codice UNSPSC: 12352104
• Numero indice EU: 204-071-0
• NACRES: NA.22
• Saggio: ≥97.0% (GC)
• P. ebollizione: 151-153 °C/1013 hPa
• Tensione di vapore: 1.3 hPa ( 20 °C)

Proprietà

• Tensione di vapore: 1.3 hPa ( 20 °C)
• Livello qualitativo: 200
• Saggio: ≥97.0% (GC)
• Stato: liquid
• Temp. autoaccensione: 151 °C
• Potenza: 600 mg/kg LD₅₀, oral (Rat)
• pH: 5-6 (20 °C in H₂O, saturated solution)
• P. ebollizione: 151-153 °C/1013 hPa
• Punto di fusione: 17-18 °C
• Temp. transizione: flash point >110 °C
• Densità: 1.56 g/cm³ at 20 °C
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: ClC(Cl)(Cl)CO
• InChI: 1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2; KPWDGTGXUYRARH-UHFFFAOYSA-N

Descrizione

Applicazioni

• Assessment of EDDP Perchlorate Stability in Biological Samples: An investigation focused on the stability of methaDoneand its main metabolite, EDDP perchlorate, in oral fluids. The study highlighted the importance of understanding metabolite stability for accurate drug testing and monitoring in forensic and clinical settings (Fucci and De Giovanni, 2008).



• EDDP Perchlorate in Drug Testing: EDDP perchlorate was examined in a forensic context using the SPME technique to simultaneously detect multiple drugs of abuse in saliva. This method underscores the utility of EDDP perchlorate as a reliable biomarker in toxicology studies and drug monitoring (Fucci, De Giovanni, and Chiarotti, 2003).



• Pharmacological Action of MethaDoneand Metabolites: Research explored the interaction of methaDoneand its metabolites, including EDDP perchlorate, with rat alpha3beta4 nicotinic receptors. These findings contribute to the understanding of the pharmacodynamic properties of methadone′s metabolites, relevant in the development of therapeutic and diagnostic strategies (Xiao et al., 2001).

Risultati analitici

Assay (GC, area%): ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.551 - 1.561
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302 - H318 - H336
• Consigli di prudenza: P261 - P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 230.0 °F - closed cup
• Punto d’infiammabilità (°C): 110 °C - closed cup