Recombinant, human transforming growth factor-β1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases.
Azioni biochim/fisiol
ED₅₀ = 0.04-0.1 ng/ml
Attenzione
Toxicity: Standard Handling (A)
Stato fisico
Lyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
Ricostituzione
Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
Reconstitute to a concentration ≥1 µg/ml in 4 mM sterile HCl containing ≥0.1% HSA or BSA.
Altre note
Shibuya, H., et al. 1996. Science272, 1179. Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA93, 5877. Lomo, J., et al. 1995. J. Immunol.154, 1634. Marushige, K., and Marushige, Y. 1995. Anticancer Res.14, 2419. Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.
Note legali
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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