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495455

Sigma-Aldrich

Oligomycin

≥90% (mixture of A, B, and C isomers, HPLC), powder, Antibiotic, Calbiochem

Sinonimo/i:

Oligomycin

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About This Item

Formula empirica (notazione di Hill):
C45H74O11
Numero CAS:
1404-19-9
Peso molecolare:
791.06
Numero MDL:
MFCD01779388
Codice UNSPSC:
12352200
NACRES:
NA.77

product name

Oligomycin, A mixture of A, B, and C isomers.

Livello qualitativo

100

Saggio

≥90% (mixture of A, B, and C isomers, HPLC)

Forma fisica

powder

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

OK to freeze

Colore

white

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+
MNULEGDCPYONBU-ZUSSGZTJSA-N

Descrizione generale

A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.

Azioni biochim/fisiol

Cell permeable: no
Primary Target
Membrane-bound mitochondrial ATPase (F1)
Product does not compete with ATP.
Reversible: no

Attenzione

Toxicity: Irritant (B)

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.

Altre note

Wolvetang, E.J., et al. 1994. FEBS Lett.339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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