V-007
O-Desmethylvenlafaxine solution
100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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About This Item
Formula empirica (notazione di Hill):
C16H25NO2
Numero CAS:
Peso molecolare:
263.38
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
Forma fisica
liquid
Caratteristiche
Snap-N-Spike®/Snap-N-Shoot®
Confezionamento
ampule of 1 mL
Produttore/marchio commerciale
Cerilliant®
Concentrazione
100 μg/mL in methanol
tecniche
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
applicazioni
clinical testing
Formato
single component solution
Temperatura di conservazione
−20°C
Stringa SMILE
OC1=CC=C(C(CN(C)C)C2(O)CCCCC2)C=C1
InChI
1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3
KYYIDSXMWOZKMP-UHFFFAOYSA-N
Informazioni sul gene
human ... SLC6A2(6530) , SLC6A4(6532)
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Categorie correlate
Descrizione generale
An analytical reference standard applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as urine drug testing, forensic analysis, or clinical toxicology. Also known as desvenlafaxine, O-desmethylvenlafaxine is an SNRI antidepressant marketed under the trade name Pristiq® for the treatment of depression. O-desmethylvenlafaxine is also a major urinary metabolite of venlafaxine, an SNRI antidepressant sold as Effexor® or Efexor and used to treat major depressive disorder, generalized anxiety disorder, and other anxiety disorders associated with depression.
Applicazioni
- Drug Stability in Pharmaceutical Formulations: Another study focused on the physical stability and solubility of O-Desmethylvenlafaxine in various pharmaceutical formulations, contributing to better drug delivery systems and enhanced therapeutic efficacy (Wang et al., 2020).
- Monitoring Drug Precursors in Advanced Treatment Processes: Research monitored N-nitrosodimethylamine (NDMA) precursors throughout membrane-based advanced wastewater treatment processes, considering the behavior of compounds like O-Desmethylvenlafaxine. This study aids in improving wastewater treatment strategies to mitigate pharmaceutical pollutants (Roccaro et al., 2020).
- Chiral Drug Analysis in Environmental Waters: A study developed a dual enantioselective LC-MS/MS method for analyzing chiral drugs in surface water, including O-Desmethylvenlafaxine. This method helps in understanding the environmental fate and behavior of chiral pharmaceuticals, enhancing environmental risk assessments (Coelho et al., 2019).
Note legali
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Effexor is a registered trademark of American Home Product Corp.
Pristiq is a registered trademark of Wyeth LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Organi bersaglio
Eyes
Codice della classe di stoccaggio
3 - Flammable liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
49.5 °F - closed cup
Punto d’infiammabilità (°C)
9.7 °C - closed cup
Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Paola C Rúa-Gómez et al.
Journal of environmental monitoring : JEM, 14(5), 1391-1399 (2012-03-27)
The presence of the anesthetic lidocaine (LDC), the analgesic tramadol (TRA), the antidepressant venlafaxine (VEN) and the metabolites O-desmethyltramadol (ODT) and O-desmethylvenlafaxine (ODV) was investigated in wastewater treatment plant (WWTP) effluents, in surface waters and in groundwater. The analytes were
Andrea Cipriani et al.
The Cochrane database of systematic reviews, 10, CD006533-CD006533 (2012-10-19)
Although pharmacological and psychological interventions are both effective for major depression, in primary and secondary care settings antidepressant drugs remain the mainstay of treatment. Amongst antidepressants many different agents are available. Duloxetine hydrochloride is a dual reuptake inhibitor of serotonin
David F Archer et al.
Menopause (New York, N.Y.), 20(1), 47-56 (2012-12-26)
A previous trial of the serotonin-norepinephrine reuptake inhibitor desvenlafaxine (administered as desvenlafaxine succinate) raised concerns on potential serious cardiovascular and hepatic events. The current study was designed to estimate these events in desvenlafaxine versus placebo in a larger population followed
S Unterecker et al.
Pharmacopsychiatry, 45(6), 229-235 (2012-03-20)
Venlafaxine (VEN) is a modern antidepressant which exerts both serotonin and norepinephrine reuptake inhibition. In this study we examined the influence of age, sex, smoking, and co-medication on serum levels of VEN and its metabolite O-desmethylvenlafaxine (ODVEN) in patients treated
Joshua Z Rosenthal et al.
The Journal of clinical psychiatry, 74(2), 158-166 (2013-03-12)
To evaluate the long-term (11-month) efficacy and safety of desvenlafaxine (administered as desvenlafaxine succinate) at the recommended 50-mg/d dose in preventing relapse in patients with major depressive disorder (MDD). Adult outpatients (age ≥ 18 years) with MDD (DSM-IV criteria) and
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