850468P

18:0-18:2 PC

1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine, powder

• Sinonimo/i: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(18:0/18:2(9Z,12Z))
• Formula empirica (notazione di Hill): C₄₄H₈₄NO₈P
• Numero CAS: 27098-24-4
• Peso molecolare: 786.11
• Numero MDL: MFCD00674330
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Stato: powder
• Confezionamento: pkg of 2 × 100 mg (850468P-200mg); pkg of 1 × 25 mg (850468P-25mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 850468P
• Tipo di lipide: phospholipids; cardiolipins
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,42H,6-14,16,18-20,22,24-41H2,1-5H3/b17-15-,23-21-/t42-/m1/s1; FORFDCPQKJHEBF-VPUSDGANSA-N

Descrizione

Descrizione generale

18:0-18:2 phosphatidylcholine (PC) has a saturated fatty acid at the sn-1 position, unsaturated fatty acid at the sn-2 position and phosphate-containing polar group at the sn-3 position.[1] PC is a zwitterionic phospholipid. PC is synthesized by Kennedy pathway from choline.[2]

Applicazioni

18:0-18:2 PC is suitable for use:

• in the preparation of large unilamellar vesicles[1]
• in the preparation of liposomes[3]
• to prepare oxidised phospholipid by 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) for multiple reaction monitoring (MRM) analysis[4]

Azioni biochim/fisiol

Phosphatidylcholine is one of the major glycerophospholipids of the eukaryotic membranes. It is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol.[2]

Confezionamento

5 mL Clear Glass Sealed Ampule (850468P-200mg)

5 mL Clear Glass Sealed Ampule (850468P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids