E33505

Ethyl isonipecotate

98%

• Sinonimo/i: Ethyl 4-piperidinecarboxylate, Piperidin-4-carboxylic acid ethyl ester
• Formula empirica (notazione di Hill): C₈H₁₅NO₂
• Numero CAS: 1126-09-6
• Peso molecolare: 157.21
• Beilstein: 118419
• Numero CE: 214-416-7
• Numero MDL: MFCD00006003
• Codice UNSPSC: 12352100
• ID PubChem: 24894508
• NACRES: NA.22

Proprietà

• Saggio: 98%
• Forma fisica: liquid
• Indice di rifrazione: n20/D 1.459 (lit.)
• P. eboll.: 204 °C (lit.)
• Densità: 1.02 g/mL at 25 °C (lit.)
• Stringa SMILE: CCOC(=O)C1CCNCC1
• InChI: 1S/C8H15NO2/c1-2-11-8(10)7-3-5-9-6-4-7/h7,9H,2-6H2,1H3; RUJPPJYDHHAEEK-UHFFFAOYSA-N

Descrizione

Applicazioni

Reactant for synthesis of:

• SMN protein modulators
• β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition
• Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone
• RhoA inhibitors for cardiovascular disease therapy
• Saccharin derived Mannich bases as antimicrobials and antioxidants

Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 176.0 °F - closed cup
• Punto d’infiammabilità (°C): 80 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)