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B1253

Sigma-Aldrich

Butylated hydroxyanisole

≥98.5%

Sinonimo/i:

2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA

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About This Item

Formula condensata:
(CH3)3CC6H3(OCH3)OH
Numero CAS:
25013-16-5
Peso molecolare:
180.24
Numero CE:
246-563-8
Numero MDL:
MFCD01779059
Codice UNSPSC:
12352100
NACRES:
NA.22

Densità del vapore

6.2 (vs air)

Livello qualitativo

200

Saggio

≥98.5%

Forma fisica

powder

Temp. autoaccensione

599 °F

Punto di fusione

58-60 °C (lit.)

InChI

1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
MRBKEAMVRSLQPH-UHFFFAOYSA-N

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Descrizione generale

Butylated hydroxyanisole is mainly used as a synthetic antioxidant in food and cosmetics. It is being extensively studied for potential toxicity.

Applicazioni

  • Antioxidant peptides from silk protein: Research explores the purification of novel antioxidant peptides derived from Bombyx mori pupae, identifying potential antioxidant applications for butylated hydroxyanisole in the food and cosmetic industries (Chukiatsiri et al., 2024).
  • Industrial lubricant additive: The performance of olive oil-based blended esters with butylated hydroxyanisole is evaluated, showcasing its efficacy as an industrial lubricant additive and its optimization using response surface methodology (Thangaraj et al., 2024).
  • Environmental degradation studies: Investigates the degradation of butylated hydroxyanisole using advanced oxidation processes, providing insights into environmental safety and the compound′s stability in pharmaceutical and industrial applications (Shi et al., 2024).

Altre note

Mixed isomers (minimum 90% 3-isomer/9% 2-isomer)

Pittogrammi

Environment
GHS09

Indicazioni di pericolo

H411

Consigli di prudenza

P273 - P391 - P501

Classi di pericolo

Aquatic Chronic 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

241.9 °F - Pensky-Martens closed cup

Punto d’infiammabilità (°C)

116.6 °C - Pensky-Martens closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

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Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes
Thompson, David and Moldeus, Peter
Biochemical Pharmacology, 37(11), 2201-2207 (1988)
Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene.
A L Branen
Journal of the American Oil Chemists' Society, 52(2), 59-63 (1975-02-01)
Stefanie D Roth et al.
PloS one, 7(9), e44505-e44505 (2012-09-14)
Inefficient intracellular protein trafficking is a critical issue in the pathogenesis of a variety of diseases and in recombinant protein production. Here we investigated the trafficking of factor VIII (FVIII), which is affected in the coagulation disorder hemophilia A. We
Bhupendra Singh et al.
Carcinogenesis, 33(12), 2601-2610 (2012-10-03)
Epidemiological data and studies in rodent models strongly support the role of estrogens in the development of breast cancers. Oxidative stress has been implicated in this carcinogenic process. We have recently demonstrated that antioxidants vitamin C or butylated hydroxyanisole (BHA)
Yann Malato et al.
Gastroenterology, 143(6), 1597-1608 (2012-08-28)
The transcription factor nuclear factor κB (NF-κB) is activated by the IκB kinase complex. The regulatory subunit of this complex, NF-κB essential modifier (NEMO or IKBKG), is a tumor suppressor. Hepatocyte-specific deletion of NEMO induces chronic liver inflammation that leads
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