925659
Poly(ethylene glycol)-block-poly(lactide-alt-glycolide)
PEG average Mn 5,000, PLGA Mn 15,000
Sinonimo/i:
PEG-PLGA
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1 G
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1 G
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About This Item
Formula condensata:
CH3O(C2H4O)n(C5H6O4)mH
Codice UNSPSC:
12352112
NACRES:
NA.23
Prodotti consigliati
Stato
powder, chunks or granules
Livello qualitativo
PM
PEG average Mn 5,000
PLGA Mn 15,000
Temperatura di conservazione
2-8°C
Categorie correlate
Applicazioni
PEG-PLGA, is a biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications.
Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.
Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.
Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Keru Zhang et al.
Journal of controlled release : official journal of the Controlled Release Society, 183, 77-86 (2014-03-29)
In the paper, we begin by describing polyethylene glycol-poly lactic acid-co-glycolic acid (PEG-PLGA) which was chosen as a typical model copolymer for the construction of nano-sized drug delivery systems and also the types of PEG-PLGA copolymers that were eluted. Following
Lin Yu et al.
Biomacromolecules, 12(4), 1290-1297 (2011-03-03)
This paper reports the influence of sequence structures of block copolymers composed of poly(lactic acid-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) on their thermogelling aqueous behaviors. A series of thermogelling PLGA-PEG-PLGA triblock copolymers with similar chemical compositions and block lengths
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