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776130

Sigma-Aldrich

3-Azido-1-propanol

≥96%

Sinonimo/i:

1-Azidopropan-3-ol

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About This Item

Formula empirica (notazione di Hill):
C3H7N3O
Numero CAS:
72320-38-8
Peso molecolare:
101.11
Numero MDL:
MFCD14652506
Codice UNSPSC:
12352125
ID PubChem:
329767811
NACRES:
NA.22
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Saggio

≥96%

Stato

liquid

Impiego in reazioni chimiche

reaction type: click chemistry

Indice di rifrazione

n20/D 1.461

Densità

1.095 g/mL at 25 °C

Temperatura di conservazione

2-8°C

Stringa SMILE

OCCCN=[N+]=[N-]

InChI

1S/C3H7N3O/c4-6-5-2-1-3-7/h7H,1-3H2
WHVSIWLMCCGHFW-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

3-Azido-1-propanol is an azide-containing reagent utilized in Strain-Promoted Azide-Alkyne Cycloaddition reactions (SPAAC). This enables selective and copper-free click chemistry modifications of biomolecules.[1]

Applicazioni

3-Azido-1-propanol is used as a:
  • Precursor in the synthesis of heterocyclic compounds like dihydrooxazines[2]
  • Reagent in the synthesis of heterofunctional polyesters by 1,3-dipolar cycloaddition[3]

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

190.0 °F

Punto d’infiammabilità (°C)

87.77 °C

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Certificati d'analisi (COA)

Lot/Batch Number
0000425008
0000425008
0000417587
0000417587
0000406585

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1, 3-Dipolar and Diels-Alder cycloaddition reactions on polyester backbones possessing internal electron-deficient alkyne moieties
M Cetin
Polym. Chem., 7, 7094-7100 (2016)
1, 3-Dipolar and Diels-Alder cycloaddition reactions on polyester backbones possessing internal electron-deficient alkyne moieties
Cetin M, et al.
Polym. Chem., 7(46), 7094-7100 (2016)
Efficient synthesis of linear multifunctional poly (ethylene glycol) by copper (I)-catalyzed Huisgen 1, 3-dipolar cycloaddition
Liu X-M, et al.
Biomacromolecules, 8(9), 2653-2658 (2007)
SPAAC-NAD-seq, a sensitive and accurate method to profile NAD+-capped transcripts
H Hu, et al.
Proceedings of the National Academy of Sciences, 118, e2025595118-e2025595118 (2021)
Cross-linked polymer-blend gate dielectrics through thermal click chemistry
Li S, et al.
Chemistry?A European Journal , 21(49), 17762-17768 (2015)
Visualizza tutti i documenti correlati

Articoli

Click Chemistry in Drug Discovery

Explore the principles and applications of click chemistry in drug discovery, highlighting efficient reactions that streamline the synthesis of bioactive compounds.

Domande

1–2 di 2 domande  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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