730300
Methacrylic acid N-hydroxysuccinimide ester
98%
Sinonimo/i:
N-(Methacryloxy)succinimide, N-(Methacryloyloxy)succinimide
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1 G
96,40 €
5 G
334,00 €
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Cambia visualizzazione
1 G
96,40 €
5 G
334,00 €
About This Item
Formula empirica (notazione di Hill):
C8H9NO4
Numero CAS:
Peso molecolare:
183.16
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23
Prodotti consigliati
Livello qualitativo
Saggio
98%
Stato
solid
Punto di fusione
101-105 °C
Temperatura di conservazione
2-8°C
Stringa SMILE
CC(=C)C(=O)ON1C(=O)CCC1=O
InChI
1S/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3
ACGJEMXWUYWELU-UHFFFAOYSA-N
Descrizione generale
Methacrylic acid N-hydroxysuccinimide ester(NHS-MA) belongs to the class of reactive monomers known as N-hydroxysuccinimide (NHS) esters. It is commonly used for functionalizing biomolecules through amine-reactive coupling reactions infields such as bioconjugation, protein labeling, and peptide synthesis. It also serves as a crosslinking agent or linker molecule for the conjugation of drugs or targeting ligands to carrier materials.
Applicazioni
Methacrylic acid N-hydroxysuccinimide ester can be used:
- As a monomer to prepare degradable amphiphilic diblock copolymer microparticles via RAFT polymerization, for low pH-triggered drug delivery. NHS-MA can shield the drug molecule from degradation, enhance its solubility, and improve its pharmacokinetic properties.[1]
- For the surface functionalization of poly-ε-caprolactone (PCL) scaffolds used for tissue engineering. NHS groups are used to couple with chitosan of various molecular weights.[2]
- To prepare biocompatible polymer hydrogel for enzymatic biofuel cells. The hydrogel can serve as an enzyme-immobilizing matrix for enzymatic bioelectrodes.[3]
Avvertenze
Warning
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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