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649317

Sigma-Aldrich

(R)-(+)-2-Methyl-CBS-oxazaborolidine

Sinonimo/i:

(R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole, (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole, (R)-Me-Corey-Bakshi-Shibata catalyst

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1 G
54,04 €
10 G
311,00 €

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Cambia visualizzazione
1 G
54,04 €
10 G
311,00 €

About This Item

Formula empirica (notazione di Hill):
C18H20BNO
Numero CAS:
Peso molecolare:
277.17
Numero MDL:
Codice UNSPSC:
12352005
ID PubChem:
NACRES:
NA.22

54,04 €

Prezzo di listino77,20 €Risparmia il 30%

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Saggio

≥90%

Livello qualitativo

Stato

solid

Punto di fusione

85-95 °C (lit.)

Gruppo funzionale

phenyl

Stringa SMILE

CB1OC(C2CCCN12)(c3ccccc3)c4ccccc4

InChI

1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1
VMKAFJQFKBASMU-QGZVFWFLSA-N

Applicazioni

The CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst has been used in the asymmetric reduction of prochiral ketones.[1][2][3] Other applications include the enantioselective synthesis of α-hydroxy acids,[4][5] α-amino acids,[6][7] C2 symmetrical ferrocenyl diols,[8] and propargyl alcohols.[9][10]

Pittogrammi

CorrosionExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

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I clienti hanno visto anche

Sing, V. K.
Synthesis, 605-605 (1992)
Corey, E. J. et al.
Journal of the American Chemical Society, 109, 5551-5551 (1987)
Schwink, L.; Knochel, P.
Tetrahedron Letters, 37, 25-25 (1996)
Togni, A.; Venanzi, L. M.
Angewandte Chemie (International Edition in English), 33, 497-497 (1994)
Corey, E. J.; Link, J. O.
Tetrahedron Letters, 33, 3431-3431 (1992)

Articoli

we are pleased to offer both enatiomers of 2-methyl-CBS-oxazaborolidine as a dry reagent, in addition to our current offerings as a 1M solution in toluene.

Learn about the applications of chiral oxazaborolidinium ions (COBIs) as Lewis acid catalysts in different asymmetric reactions such as cyclopropanation, epoxidation, and radical reactions along with details of their catalytic action.

Domande

1–2 di 2 domande  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

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