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61250

Sigma-Aldrich

DL-Kynurenine

≥95.0% (NT), for peptide synthesis

Sinonimo/i:

2-Amino-3-(2-aminobenzoyl)propionic acid, 2-Amino-4-(2-aminophenyl)-4-oxobutyric acid

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About This Item

Formula empirica (notazione di Hill):
C10H12N2O3
Numero CAS:
343-65-7
Peso molecolare:
208.21
Beilstein:
2697333
Numero CE:
206-445-9
Numero MDL:
MFCD00025194
Codice UNSPSC:
12352209
ID PubChem:
57651839
NACRES:
NA.22

product name

DL-Kynurenine, ≥95.0% (NT)

Saggio

≥95.0% (NT)

Forma fisica

powder

Punto di fusione

~235 °C (dec.)

applicazioni

peptide synthesis

Stringa SMILE

NC(CC(=O)c1ccccc1N)C(O)=O

InChI

1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)
YGPSJZOEDVAXAB-UHFFFAOYSA-N

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Categorie correlate

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Rahul Shinde et al.
Nature immunology, 19(6), 571-582 (2018-05-16)
The transcription factor AhR modulates immunity at multiple levels. Here we report that phagocytes exposed to apoptotic cells exhibited rapid activation of AhR, which drove production of the cytokine IL-10. Activation of AhR was dependent on interactions between apoptotic-cell DNA
Adam K Walker et al.
Molecular psychiatry, 24(10), 1523-1532 (2018-07-11)
Inflammation activates indoleamine 2,3-dioxygenase (IDO) which metabolizes tryptophan into kynurenine. Circulating kynurenine is transported into the brain by the large amino transporter LAT1 at the level of the blood-brain barrier. We hypothesized that administration of leucine that has a high
Alban Bessede et al.
Nature, 511(7508), 184-190 (2014-06-17)
Disease tolerance is the ability of the host to reduce the effect of infection on host fitness. Analysis of disease tolerance pathways could provide new approaches for treating infections and other inflammatory diseases. Typically, an initial exposure to bacterial lipopolysaccharide
Adam Kosti et al.
Genome biology, 21(1), 195-195 (2020-08-09)
RNA-binding proteins (RBPs) function as master regulators of gene expression. Alterations in RBP expression and function are often observed in cancer and influence critical pathways implicated in tumor initiation and growth. Identification and characterization of oncogenic RBPs and their regulatory
Dag Holmberg et al.
Malaria journal, 16(1), 303-303 (2017-07-30)
One-fourth of children with cerebral malaria (CM) retain cognitive sequelae up to 2 years after acute disease. The kynurenine pathway of the brain, forming neuroactive metabolites, e.g. the NMDA-receptor antagonist kynurenic acid (KYNA), has been implicated in long-term cognitive dysfunction in
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