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543292

Sigma-Aldrich

IR-783

Dye content 90 %

Sinonimo/i:

2-[2-[2-Chloro-3-[2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium hydroxide, inner salt sodium salt

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250 MG
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Cambia visualizzazione
250 MG
91,50 €

About This Item

Formula empirica (notazione di Hill):
C38H46ClN2NaO6S2
Numero CAS:
Peso molecolare:
749.35
Numero MDL:
Codice UNSPSC:
12352103
ID PubChem:
NACRES:
NA.23

91,50 €


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Stato

solid

Livello qualitativo

Composizione

Dye content, 90%

Punto di fusione

209-212 °C (lit.)

λmax

782 nm

Stringa SMILE

[Na+].CC1(C)\C(=C\C=C2/CCCC(\C=C\C3=[N+](CCCCS([O-])(=O)=O)c4ccccc4C3(C)C)=C2Cl)N(CCCCS([O-])(=O)=O)c5ccccc15

InChI

1S/C38H47ClN2O6S2.Na/c1-37(2)30-16-5-7-18-32(30)40(24-9-11-26-48(42,43)44)34(37)22-20-28-14-13-15-29(36(28)39)21-23-35-38(3,4)31-17-6-8-19-33(31)41(35)25-10-12-27-49(45,46)47;/h5-8,16-23H,9-15,24-27H2,1-4H3,(H-,42,43,44,45,46,47);/q;+1/p-1
QQIQAVJARACLHE-UHFFFAOYSA-M

Descrizione generale

IR-783 is a near-infrared (NIR) dye with an extinction coefficient of 157000 M−1cm−1 and quantum yield of 0.11. Its excitation wavelength is in the range of 768-784 nm in saline.[1]

Applicazioni

IR-783 can be used as a starting material in the synthesis of IR-808 dye for biological applications.[2] It can also be used in the formation of NIR fluorescent human serum albumin nanoparticles for the detection of a tumor.[3] It finds potential usage as a contrasting agent for the multimodal in vivo imaging.[4]

Caratteristiche e vantaggi

Water soluble, laser and near-IR dye

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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I clienti hanno visto anche

Synthesis and characterization of near IR fluorescent albumin nanoparticles for optical detection of colon cancer
Cohen S, et al.
Materials Science and Engineering, C, 33(2), 923-931 (2013)
Multimeric near IR-MR contrast agent for multimodal in vivo imaging
Harrison VSR, et al.
Journal of the American Chemical Society, 137(28), 9108-9116 (2015)
Lily Yang et al.
Theranostics, 4(1), 106-118 (2014-01-08)
Complete removal of tumors by surgery is the most important prognostic factor for cancer patients with the early stage cancers. The ability to identify invasive tumor edges of the primary tumor, locally invaded small tumor lesions, and drug resistant residual
2-[2-[2-Chloro-3-[2-[1, 3-dihydro-3, 3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-3, 3-dimethyl-1-(4-sulfobutyl)-3H-indolium
Molecular Imaging and Contrast Agent Database (MICAD) (2010)
Guanjun Deng et al.
Theranostics, 8(15), 4116-4128 (2018-08-22)
Near-infrared (NIR) fluorescence imaging has relied on fluorophores that emit in the 700-900 nm NIR-Ia or 1,000-1,700 nm NIR-II window for generating deep-tissue images. Up until now, there have been few fluorophores developed for the 900-1,000 nm NIR-Ib window. This

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Domande

1–4 di 4 domande  
  1. How should it be stored?

    1 risposta
    1. This product may be stored in room temperature. This product should be stored tightly closed in a dry place.

      Utile?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  4. Could you provide the expected absorption spectrum for IR-783?

    1 risposta
    1. The absorption maximum for product 543292 is 783 nm in methanol.

      Utile?

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