498289

3-Ethynylaniline

≥98%

• Formula condensata: HC≡CC₆H₄NH₂
• Numero CAS: 54060-30-9
• Peso molecolare: 117.15
• Numero CE: 258-944-6
• Numero MDL: MFCD00014779
• Codice UNSPSC: 12352100
• ID PubChem: 24873187
• NACRES: NA.22

Proprietà

• Saggio: ≥98%
• Impiego in reazioni chimiche: reaction type: click chemistry
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Nc1cccc(c1)C#C
• InChI: 1S/C8H7N/c1-2-7-4-3-5-8(9)6-7/h1,3-6H,9H2; NNKQLUVBPJEUOR-UHFFFAOYSA-N

Descrizione

Descrizione generale

3-Ethynylaniline is a terminal alkyne that can be prepared by the reduction of 3-ethylnylnitrobenzene.

Applicazioni

3-Ethynylaniline may be used in the synthesis of the following benzoxazine monomers:

• bis{4-[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yloxy)]phenyl}phenylphosphino-1-one
• [3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazaperhydroin-6-yl)][3-(3-ethynylphenyl)(2H,4H-benzo[3,4-e]1,3-oxazin-6-yl)]phenylphosphino-1-one
• bis[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yl)oxy]phenylphosphino-1-one

It may be used:

• To synthesize succin(m-ethynyl)dianilide and sebaco(m-ethynyl)dianilide.
• As a reagent in the multi-step synthesis of erlotinib hydrochloride.
• To prepare 3-(3-ethynylphenyl)-6-methyl-2H, 4H-benzo[e]1,3-oxazine.
• To prepare 3-[3-(4-acetylamino-benzyl)-[1,2,4]oxadiazol-5- yl]-N-(3-ethynyl-phenyl)-propionamide.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H226,H315,H319,H335
• Consigli di prudenza: P210 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 138.2 °F - closed cup
• Punto d’infiammabilità (°C): 59 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type ABEK (EN14387) respirator filter