254606

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

96%

• Sinonimo/i: α,β-Isopropylidene-L-glyceric acid methyl ester, Methyl α,β-isopropylidene-L-glycerate, Methyl 2,3-O-isopropylidene-L-glycerate
• Formula empirica (notazione di Hill): C₇H₁₂O₄
• Numero CAS: 60456-21-5
• Peso molecolare: 160.17
• Beilstein: 4292352
• Numero MDL: MFCD00066526
• Codice UNSPSC: 12352005
• ID PubChem: 24855396
• NACRES: NA.22

Proprietà

• Livello qualitativo: 200
• Saggio: 96%
• Stato: liquid
• Attività ottica: [α]20/D −8.5°, c = 1.5 in acetone
• Purezza ottica: ee: ≥96.0% (GLC)
• Indice di rifrazione: n20/D 1.425 (lit.)
• P. ebollizione: 84-86 °C/15 mmHg (lit.)
• Densità: 1.106 g/mL at 25 °C (lit.)
• Gruppo funzionale: ester; ether; ketal
• Stringa SMILE: COC(=O)[C@@H]1COC(C)(C)O1
• InChI: 1S/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m0/s1; DOWWCCDWPKGNGX-YFKPBYRVSA-N

Descrizione

Applicazioni

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate can be used:

• As a chiral building block to make the key tetrahydrofuran subunit of (−)-gymnodimine, a marine algal toxin.[1]
• To prepare an enedione by reacting with dimethyl methylphosphonate, BuLi, and phenylglyoxal, which in turn is used to synthesize cyclopentenone derivatives.[2]
• As a starting material for the preparation of (S)-4,5-dihydroxy-2,3-pentanedione (DPD), a precursor for autoinducer (AI)-2 in bacteria.[3]

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 172.4 °F - closed cup
• Punto d’infiammabilità (°C): 78 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type ABEK (EN14387) respirator filter