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240702

Sigma-Aldrich

Ethyl acetoacetate

≥99%

Sinonimo/i:

Acetoacetic ester

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About This Item

Formula condensata:
CH3COCH2COOC2H5
Numero CAS:
Peso molecolare:
130.14
Beilstein:
385838
Numero CE:
Numero MDL:
Codice UNSPSC:
12352103
ID PubChem:

Densità del vapore

4.48 (vs air)

Tensione di vapore

1 mmHg ( 28.5 °C)

Saggio

≥99%

Temp. autoaccensione

580 °F

Limite di esplosione

9.5 %

P. ebollizione

181 °C (lit.)

Punto di fusione

−43 °C (lit.)

Densità

1.029 g/mL at 20 °C (lit.)

Stringa SMILE

CCOC(=O)CC(C)=O

InChI

1S/C6H10O3/c1-3-9-6(8)4-5(2)7/h3-4H2,1-2H3
XYIBRDXRRQCHLP-UHFFFAOYSA-N

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Descrizione
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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

164.3 °F - closed cup

Punto d’infiammabilità (°C)

73.5 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Junguo Xin et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 14(10), 3177-3181 (2008-02-05)
An enantioselective Biginelli reaction that proceeds by a dual-activation route has been developed by using a combined catalyst of a readily available trans-4-hydroxyproline-derived secondary amine and a Brønsted acid. Aromatic, heteroaromatic, and fused-ring aldehydes were found to be suitable substrates
Hassan Valizadeh et al.
Molecular diversity, 15(1), 233-237 (2010-07-24)
In this study, a three-component one-pot synthesis of select 5-amino-6-cyano-3-hydroxybenzo[c]coumarin compounds derived from salicylaldehydes, malononitrile, and ethyl acetoacetate is reported. The reaction is conducted on grinding over MgO at room temperature resulting in good yields.
Arne T Dickschat et al.
Chemical communications (Cambridge, England), 49(22), 2195-2197 (2013-02-09)
Bifunctional mesoporous silica nanoparticles (MSNs) bearing Pd-complexes and additional basic sites were prepared and tested as cooperative active catalysts in the Tsuji-Trost allylation of ethyl acetoacetate. Functionalization of the MSNs was realized by postmodification using click-chemistry. The selectivity of mono
Debasish Bandyopadhyay et al.
Molecules (Basel, Switzerland), 17(3), 2643-2662 (2012-03-07)
The classical Hantzsch reaction is one of the simplest and most economical methods for the synthesis of biologically important and pharmacologically useful 1,4-dihydropyridine derivatives. Bismuth nitrate pentahydrate under microwave irradiation is proven to act as a very efficient catalyst for
Gui-Rong Qu et al.
Organic letters, 11(8), 1745-1748 (2009-03-20)
A novel approach to the synthesis of purines bearing functionalized carbon substituents or methyl in position 6 was developed. Under different reaction conditions, 6-halopurine derivatives could react with ethyl acetoacetate efficiently to yield 2-(purin-6-yl)acetoacetic acid ethyl esters, (purin-6-yl)acetates and 6-methylpurines

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