Passa al contenuto
Merck
  • New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions.

New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions.

Molecular diversity (2010-07-24)
Hassan Valizadeh, Ashraf Fakhari
ABSTRACT

In this study, a three-component one-pot synthesis of select 5-amino-6-cyano-3-hydroxybenzo[c]coumarin compounds derived from salicylaldehydes, malononitrile, and ethyl acetoacetate is reported. The reaction is conducted on grinding over MgO at room temperature resulting in good yields.

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
Ethyl acetoacetate, ReagentPlus®, 99%
Sigma-Aldrich
Ethyl acetoacetate, natural, ≥97%, FG
Sigma-Aldrich
Ethyl acetoacetate, ≥99%, FCC, FG
Sigma-Aldrich
Ethyl acetoacetate, puriss. p.a., ≥99.0% (GC)
Sigma-Aldrich
Ethyl acetoacetate, Arxada quality, ≥99.0% (GC)