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153818

Sigma-Aldrich

2-Adamantylamine hydrochloride

99%

Sinonimo/i:

2-Adamantanamine hydrochloride, 2-Aminoadamantane hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C10H17N · HCl
Numero CAS:
10523-68-9
Peso molecolare:
187.71
Beilstein:
4297901
Numero CE:
234-074-2
Numero MDL:
MFCD00074743
Codice UNSPSC:
12352100
ID PubChem:
24849376
NACRES:
NA.22

Saggio

99%

Forma fisica

solid

Punto di fusione

>300 °C (lit.)

Stringa SMILE

Cl.NC1[C@@H]2C[C@H]3C[C@@H](C2)C[C@@H]1C3

InChI

1S/C10H17N.ClH/c11-10-8-2-6-1-7(4-8)5-9(10)3-6;/h6-10H,1-5,11H2;1H/t6-,7+,8-,9+,10?;
WLDWDRZITJEWRJ-ZDAMNCSYSA-N

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Descrizione generale

The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied.

Applicazioni

2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2′-(carboxymethoxime)-olivomycin I.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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S V Krapivin et al.
Biulleten' eksperimental'noi biologii i meditsiny, 116(11), 515-518 (1993-11-01)
The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated. Bromantane leads to decreases in
Alina A Okhina et al.
Journal of pharmaceutical and biomedical analysis, 180, 113039-113039 (2019-12-23)
A method of quantitative determination of camphecene, a new anti-influenza agent, in rat blood plasma based on LC-MS/MS was developed, validated and used to study the distribution of the agent between blood cells and blood plasma. The method was validated
Anna N Tevyashova et al.
The Journal of antibiotics, 62(1), 37-41 (2009-01-10)
A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine hemihydrochloride gave the key intermediate, 2'-carboxymethoxime-olivomycin I, which
C Clark et al.
Immunopharmacology, 21(1), 41-50 (1991-01-01)
The present in vitro investigations on amantadine (AmTd) and its isomer 2-aminoadamantane (2-NH2-Adam), and the corresponding analogs, 1-nitroadamantane (1-NO2-Adam) and 2-nitroadamantane (2-NO2-Adam), were undertaken to gain information about molecular features that might have a dominant role in inhibiting T lymphocyte
Yasuhiko Higashi et al.
Biomedical chromatography : BMC, 20(5), 423-428 (2005-09-15)
Simultaneous HPLC assay of 1-adamantanamine hydrochloride (amantadine) and its four related compounds [2-adamantanamine hydrochloride (2-ADA), 1-adamantanmethylamine (ADAMA), 1-(1-adamantyl)ethylamine hydrochloride (rimantadine) and 3,5-dimethyl-1-adamantanamine hydrochloride (memantine)] in phosphate-buffered saline (pH 7.4) after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) was developed. Phosphate-buffered saline samples
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