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Merck

BRD2

bromodomain containing 2

Sinonimi:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
Specie:
ID UniProtKB:
ID gene:
  • Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(14312) bromodomain containing 2
  • Rat(294276) bromodomain containing 2
  • domestic guinea pig(100734555) bromodomain containing 2
  • cow(505358) bromodomain containing 2
  • Domestic Rabbit(100343906) bromodomain containing 2
  • domestic cat(101084362) bromodomain containing 2
  • sheep(101110276) bromodomain containing 2
  • chicken(417049) bromodomain containing 2
  • dog(474868) bromodomain containing 2
  • naked mole-rat(101699681) bromodomain containing 2

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-BRD2 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-BRD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, rat
Applicazione
immunohistochemistry
western blot
Goat anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reattività con
human
Applicazione
western blot
Rabbit anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
I-BET762, ≥98% (HPLC),
Specie
human
OTX015, ≥98% (HPLC),
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
BRD2, BD1, BD2 (65-459) GST tag human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human
BRD2 (339-459) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Specie
human
BRD2 (65-187) GST tag human, recombinant, expressed in E. coli, ≥81% (SDS-PAGE),
Specie
human
BRD2 (65-187) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Specie
human
BRD2 (339-459) GST tag human, recombinant, expressed in E. coli, ≥86% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Brd2,
Specie
mouse
MISSION® esiRNA, targeting human BRD2,
Specie
human