SAB4300072

Anti-phospho-TP53 (pSer⁶) antibody produced in rabbit

affinity isolated antibody

• Szinonimák: Anti-FLJ92943 antibody produced in rabbit, Anti-LFS1 antibody produced in rabbit, Anti-TRP53 antibody produced in rabbit, Anti-p53 antibody produced in rabbit, Anti-tumor protein p53 antibody produced in rabbit
• MDL-szám: MFCD00164709
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• molekulatömeg: ~53 kDa
• faj reaktivitás: human
• koncentráció: 1 mg/mL
• technika/technikák: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• izotípus: IgG
• immunogén szekvencia: (P-Q-SP-D-P)
• NCBI elérési szám: NP_000537.3
• UniProt elérési szám: P04637
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: phosphorylation (pSer6)
• Géninformáció: human ... TP53(7157)

Leírás

Immunogen

Peptide sequence around phosphorylation site of serine 6 (P-Q-S(p)-D-P), according to the protein TP53.

Tulajdonságok és előnyök

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Cél megnevezése

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.

Fizikai forma

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable