8.52108

Fmoc-Ala-(Dmb)Gly-OH

≥97.0% (HPLC), for peptide synthesis, Novabiochem^®

• Szinonimák: Fmoc-Ala-(Dmb)Gly-OH, N-α-Fmoc-L-alanyl-N-α-(2, 4-dimethoxybenzyl)-glycine
• Tapasztalati képlet (Hill-képlet): C₂₉H₃₀N₂O₇
• Molekulatömeg: 518.56
• UNSPSC kód: 12352209
• NACRES: NA.22

Tulajdonságok

• product name: Fmoc-Ala-(Dmb)Gly-OH, Novabiochem^®
• Minőségi szint: 200
• termékcsalád: Novabiochem^®
• Teszt: ≥90.0% (acidimetric); ≥97% (TLC); ≥97.0% (HPLC)
• form: powder
• reakcióalkalmasság: reaction type: Fmoc solid-phase peptide synthesis
• gyártó/kereskedő neve: Novabiochem^®
• alkalmazás(ok): peptide synthesis
• funkcionális csoport: Fmoc
• tárolási hőmérséklet: 2-8°C

Leírás

Általános leírás

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP^® /DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

Kapcsolódás

Replaces: 04-12-1265

Analízis megjegyzés

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -26.5 - -21.5 °
Purity (TLC(0811)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 2.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Jogi információk

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable