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Merck

1033000

USP

氨苄西林

United States Pharmacopeia (USP) Reference Standard

别名:

D-(−)-α-氨苄青霉素

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About This Item

经验公式(希尔记法):
C16H19N3O4S
CAS号:
分子量:
349.40
Beilstein:
1090925
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

描述

API family: ampicillin

API 家族

ampicillin

製造商/商標名

USP

mp

208 °C (dec.) (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3)C(O)=O

InChI

1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1

InChI 密鑰

AVKUERGKIZMTKX-NJBDSQKTSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Ampicillin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Ampicillin Sodium
  • Ampicillin Capsules
  • Ampicillin Tablets
  • Ampicillin Boluses
  • Ampicillin for Injection
  • Ampicillin Soluble Powder
  • Ampicillin for Oral Suspension

生化/生理作用

作用机制:氨苄西林是一种半合成的青霉素和ß-内酰胺抗生素,其通过灭活位于细菌的细胞膜内表面的转肽酶从而抑制细菌细胞壁合成。

耐药性机制:ß-内酰胺酶切开氨苄青霉素的ß-内酰胺环,使其失去活性。

抗菌谱:对革兰氏阳性菌(类似于苄青霉素)和革兰氏阴性菌(类似于四环素和氯霉素)均有效。

注意

This product has been reported stable as supplied at 25°C at 43% and 81% relative humidity for six weeks. Additional studies have shown that the stability of Ampicillin in solution is a function of pH, temperature and the identity of the buffer. It′s activity is quickly lost when stored above pH 7. Optimal storage conditions are suggested as 2-8°C, and pH 3.8-5 where its activity was retained at 90%+ for a week.

準備報告

Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized through filtration and stored frozen, where it will be stable for months.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

法律資訊

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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