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Merck

SML3845

Sigma-Aldrich

Enterocin

≥95% (HPLC)

别名:

(3R,4aR,5S,6S,7S,7aS,8R)-7-Benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-3,6-methanocyclopenta[c]pyran-1(3H)-one, Vulgamycin

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About This Item

经验公式(希尔记法):
C22H20O10
CAS号:
分子量:
444.39
分類程式碼代碼:
51111800
分類程式碼代碼:
12352200
NACRES:
NA.21

品質等級

化驗

≥95% (HPLC)

形狀

(Powder or lyophilized powder)

顏色

white to off-white

儲存溫度

-10 to -25°C

生化/生理作用

Enterocin is a bacteriostatic polyketide antibiotic unrelated to the polypeptide enterocin bacteriocins. It has broad-spectrum antibiotic activity against both gram-positive and gram-negative bacteria. Enterocin has also been shown to have inhibitory activity against β-amyloid protein (Aβ1-42) fibrillation and moderate cytotoxicity against HeLa and HepG2 cancer cell lines.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin
Journal of Natural Products, 78(3), 539-542 (2015)
Exploring Natural Product Artifacts: The Polyketide Enterocin Warms to a Ballet of Isomers
Organic Letters, 22(12), 4828-4832 (2020)
Dong-Bo Xu et al.
Applied microbiology and biotechnology, 99(14), 5825-5832 (2015-04-22)
The type II polyketide synthase (PKS) natural product enterocin (1) was isolated from a mangrove-derived novel species Streptomyces qinglanensis 172205 guided by genome sequence, and its putative biosynthetic gene cluster was revealed. Its natural analogues 5-deoxyenterocin (2) and wailupemycin A-C

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