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Merck

P2519

Sigma-Aldrich

-吡哌酸

99% (titration), suitable for GC/MS

别名:

-高脯氨酸, (S)-(& # 8722;)-2-哌啶羧酸

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About This Item

经验公式(希尔记法):
C6H11NO2
CAS号:
分子量:
129.16
Beilstein:
81093
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.26

product name

-吡哌酸, 99% (titration)

化驗

99% (titration)

形狀

powder

技術

GC/MS: suitable

顏色

white

mp

272 °C (lit.)

SMILES 字串

OC(=O)[C@@H]1CCCCN1

InChI

1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1

InChI 密鑰

HXEACLLIILLPRG-YFKPBYRVSA-N

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一般說明

L-哌啶酸(哌啶-2-羧酸)是含氮的杂环化合物。它属于亚氨基酸。分子量为129.2。

應用

L-哌啶酸已用作气相色谱-质谱分析(GC-MS)中的定量标准品。

生化/生理作用

L-哌啶酸可用于泽尔韦格氏综合征。哌啶酸也是一种植物防御代谢物。它是一种信号传导化合物,对系统获得抗性(SAR)至关重要。
L-哌啶酸是赖氨酸代谢物;其分解代谢缺陷与高磷血症、脑肝肾综合征、新生儿肾上腺脑白质营养不良和婴儿雷夫森病有关。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Donze-Reiner T, et al.
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Pipecolic acid
Laboratory Guide to the Methods in Biochemical Genetics (2008)
S J Mihalik et al.
The Journal of biological chemistry, 264(5), 2509-2517 (1989-02-15)
L-Pipecolic acid oxidation was studied in the rabbit and cynomolgus monkey. Tissue homogenates from both species incubated with L-[2,3,4,5,6-3H]pipecolic acid produced a single radioactive product identified as alpha-aminoadipic acid. In the rabbit, L-pipecolic acid oxidation was greatest in kidney cortex
S J Mihalik et al.
Pediatric research, 25(5), 548-552 (1989-05-01)
L-Pipecolic acid, a cyclic imino acid produced during the degradation of lysine, accumulates in body fluids of infants with the generalized peroxisomal disorders, including Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease. Peroxisome-enriched fractions from normal human liver oxidized L-[3H]pipecolic
Ronald J A Wanders
American journal of medical genetics. Part A, 126A(4), 355-375 (2004-04-21)
The group of peroxisomal disorders now includes 17 different disorders with Zellweger syndrome as prototype. Thanks to the explosion of new information about the functions and biogenesis of peroxisomes, the metabolic and molecular basis of most of the peroxisomal disorders

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