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表单
liquid
折射率
n20/D 1.418 (lit.)
沸点
85-86 °C/10 mmHg (lit.)
密度
1.206 g/mL at 20 °C
SMILES字符串
CCOS(C)(=O)=O
InChI
1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
InChI key
PLUBXMRUUVWRLT-UHFFFAOYSA-N
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应用
甲磺酸乙酯已用于诱导小鼠胚胎成纤维细胞、酵母人胚肾细胞系和人淋巴细胞中的突变。
生化/生理作用
甲磺酸乙酯是一种DNA乙基化剂，对植物和动物具有致突变性，并在哺乳动物中具有致癌性。它已被用作DNA修复过程研究中的一种模范的烷化剂。EMS可诱导鸟嘌呤-胞嘧啶（G/C）碱基被取代为腺嘌呤-胸腺嘧啶（A/T）。EMS还可在基因组中产生点突变和单核苷酸多态性。MES是一种潜在的化学致突变剂，用于在水稻、小麦和拟南芥中诱导突变。
警示用语：
Danger
危险分类
Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
212.0 °F
闪点(°C)
100 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
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