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Merck

K1515

Sigma-Aldrich

Anti-Kallikrein 11 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

别名:

Anti-Hippostasin, Anti-KLK11

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~35 kDa

物種活性

rat, mouse, human

濃度

~1 mg/mL

技術

immunohistochemistry: suitable
western blot: 1:500-1:1,000

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... KLK11(11012)
mouse ... Klk11(56538)
rat ... Klk11(292849)

一般說明

The gene KLK11 (kallikrein 11) encodes a member of the kallikrein gene family. The gene is mapped to human chromosome 19q13.4. It is found to be highly expressed in the prostate. It has been found to be present in biological fluids and in serum of patients with various cancers. KLK11 is also found to be expressed in stomach, trachea, skin, and colon.

免疫原

synthetic peptide corresponding to residues 68-82 of the human Kallikrein 11. This sequence is 86% identical in mouse and rat.

生化/生理作用

The gene KLK11 (kallikrein 11) encodes a putative serine protease that is overexpressed in prostate and ovarian cancer. It serves as a biomarker for prognosis of ovarian cancer. It can serve as a marker for distinguishing between prostate cancer and benign prostatic hyperplasia.

外觀

solution in phosphate buffered saline, containing 0.02% sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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访问文档库

The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Nakamura T
Cancer Research, 63, 6543-6546 (2003)
Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma.
Diamandis EP
Cancer Research, 62, 295-300 (2002)
Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients.
Diamandis EP
Clinical Biochemistry, 37, 823-829 (2004)

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