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Merck

F1177

Sigma-Aldrich

荧光素透明质酸

>95%, powder

别名:

Hyaluronic Acid Fluorescein Conjugate

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About This Item

MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

應用

荧光素透明质酸已用于透明质酸 (ha) 和葡聚糖表面涂层膜 和图案化表面的荧光成像。在共聚焦荧光显微镜中也用于定位胶原/HA 复合凝胶中的透明质酸。

生化/生理作用

利用与荧光素胺偶联的透明质酸大分子 (HA) 通过荧光相关光谱法 (FCS) 通过测量荧光素标记的 HA 片段的猝灭来筛选透明质酸酶活性。它结合在源自人肿瘤的恶性间皮瘤的细胞表面上。
用于与人类肿瘤来源的恶性间皮瘤细胞表面结合。

其他說明

来自鸡冠或通过发酵。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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T Asplund et al.
Cancer research, 54(16), 4516-4523 (1994-08-15)
Hyaluronan-binding sites were demonstrated on the cell surface of three malignant mesothelioma cell lines derived from human tumors using either [3H]hyaluronan or fluorescein-tagged hyaluronan. No hyaluronan-binding activity was observed on normal human mesothelial cells. The absence of hyaluronan receptors on
Hyaluronan receptors are expressed on human malignant mesothelioma cells but not on normal mesothelial cells
Asplund T and Heldin P
Cancer research, 54(16), 4516-4523 (1994)
Rafal Fudala et al.
Journal of photochemistry and photobiology. B, Biology, 106, 69-73 (2011-11-16)
In this report we propose a lifetime-based sensing (LBS) for the detection of hyaluronidase (HA-ase). First, we heavily label hyaluronan macromolecules (HAs) with fluorescein amine. The fluorescein labeled HA (HA-Fl) has a weak fluorescence and short fluorescence lifetime due to
Human macrophage adhesion on polysaccharide patterned surfaces
Tsai IY, et al.
Soft Matter, 7(7), 3599-3606 (2011)
Hyaluronan and dextran modified tubes resist cellular activation with blood contact
Eckmann DM, et al.
Colloids and Surfaces. B, Biointerfaces, 108, 44-51 (2013)

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