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Merck

E0516

Sigma-Aldrich

依托度酸

别名:

1,8-二乙基-1,3,4,9-四氢吡喃[3,4-b]吲哚-1-乙酸, NSC 282126, 依托度酸

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About This Item

经验公式(希尔记法):
C17H21NO3
CAS号:
分子量:
287.35
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

创始人

Wyeth

储存温度

2-8°C

SMILES字符串

CCc1cccc2c3CCOC(CC)(CC(O)=O)c3[nH]c12

InChI

1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)

InChI key

NNYBQONXHNTVIJ-UHFFFAOYSA-N

基因信息

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生化/生理作用

非甾体类抗炎化合物,其是COX-1和COX-2的非选择性抑制剂。

特点和优势

该化合物由 Wyeth 开发 。要浏览其他制药公司开发的化合物列表批准的药物/候选药物的列表, 点击这里

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Etodolac: the chemistry, pharmacology, metabolic disposition, and clinical profile of a novel anti-inflammatory pyranocarboxylic acid.
L G Humber
Medicinal research reviews, 7(1), 1-28 (1987-01-01)
Tetsuji Takayama et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 17(11), 3803-3811 (2011-03-10)
On the basis of the results of our preliminary trial suggesting that aberrant crypt foci (ACF) could be eradicated by short-term administration of sulindac, in the present study, we explored the feasibility of using ACF as surrogate markers for chemoprevention
D R Brocks et al.
Clinical pharmacokinetics, 26(4), 259-274 (1994-04-01)
Etodolac is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is marked as the racemate. Currently, the drug is available in several countries for the treatment of arthritis and the alleviation of pain. Etodolac possesses several unique disposition features mainly due
Soad S Abd el-Hay et al.
Journal of fluorescence, 22(1), 247-252 (2011-08-20)
A simple, selective and sensitive luminescence method has been developed for the assay of etodolac (I), moxepril HCl (II) and fexofenadine HCl (III) in bulk drug and pharmaceutical formulations. The method is based on the luminescence sensitization of europium (Eu(3+))
M Pena
Rheumatology international, 10 Suppl, 9-16 (1990-01-01)
Numerous clinical trials have shown etodolac to be an effective analgesic. The purpose of the present report is to review results of 14 studies that demonstrate the effectiveness of etodolac in a variety of painful conditions. Presented are the results

商品

Discover Bioactive Small Molecules for Lipid Signaling Research

Chromatograms

application for HPLC

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