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品質等級
化驗
≥50% (TLC)
形狀
powder
顏色
white to off-white
溶解度
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
儲存溫度
−20°C
SMILES 字串
[Na+].[H]C(=O)[C@H](O)[C@H](O)COP(O)([O-])=O
InChI
1S/C4H9O7P.Na/c5-1-3(6)4(7)2-11-12(8,9)10;/h1,3-4,6-7H,2H2,(H2,8,9,10);/q;+1/p-1/t3-,4+;/m0./s1
InChI 密鑰
KKDBADMPNGAKHM-RFKZQXLXSA-M
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應用
D-赤藓糖-4-磷酸(E4P)可作为底物,用于识别、区分和鉴定2-酮基-3-脱氧-6-磷酸半乳糖酸(KDPGal)醛缩酶和3-脱氧-D-阿拉伯-庚酮酸7-磷酸(DAH7P)合成酶,这两种酶用于启动微生物和植物中的莽草酸途径。可作为底物识别、区分和鉴定甘油醛-3-磷酸脱氢酶(GAPDH),这种酶参与致病微生物的表面抗原和毒力因子形成。 PLP(吡哆醛5′-磷酸)合成酶复合物负责从头合成恶性疟原虫中的维生素B6,在疟疾研究中,E4P可作为该复合物PfPdx1组分的抑制剂。
生化/生理作用
D-赤藓糖-4-磷酸作为中间产物参与磷酸戊糖途径,以及苯丙氨酸、酪氨酸、色氨酸生物合成与维生素B6代谢。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
The Biochemical journal, 390(Pt 1), 223-230 (2005-04-28)
DAH7P (3-Deoxy-D-arabino-heptulosonate 7-phosphate) synthase catalyses the condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) as the first committed step in the biosynthesis of aromatic compounds in plants and micro-organisms. Previous work has identified two families of DAH7P synthases based
Protein expression and purification, 89(2), 146-155 (2013-03-20)
The gammaproteobacterium Pseudomonas syringae pv. tomato DC3000 is the causal agent of bacterial speck, a common disease of tomato. The mode of infection of this pathogen is not well understood, but according to molecular biological, genomic and proteomic data it
The Biochemical journal, 449(1), 175-187 (2012-10-09)
Malaria tropica is a devastating infectious disease caused by Plasmodium falciparum. This parasite synthesizes vitamin B6 de novo via the PLP (pyridoxal 5'-phosphate) synthase enzymatic complex consisting of PfPdx1 and PfPdx2 proteins. Biosynthesis of PLP is largely performed by PfPdx1
Bioorganic & medicinal chemistry letters, 21(17), 5092-5097 (2011-04-16)
3-Deoxy-d-arabino-heptulosonate 7-phosphate (DAH7P) synthase catalyses the first step of the shikimate pathway for the biosynthesis of aromatic compounds. Enzymes of this pathway have been identified as potential targets for drug design. The reaction catalysed by DAH7P synthase is an aldol
Frontiers in bioscience (Landmark edition), 18, 944-969 (2013-06-12)
The shikimate pathway provides basic building blocks for a variety of aromatic compounds including aromatic amino acids, ubiquinone, folate and compounds of the secondary metabolism. The seven enzymatic reactions of the pathway lead to the generation of chorismate from simple
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