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Merck
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文件

F3627

Sigma-Aldrich

D-果糖6-磷酸 二钠盐 水合物

≥98%, amorphous powder

别名:

Sodium (2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl phosphate

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About This Item

经验公式（希尔记法）:
C6H11Na2O9P · xH2O
CAS号:
26177-86-6
分子量:
304.10 (anhydrous basis)
Beilstein:
5686786
MDL號碼:
MFCD16661244
分類程式碼代碼:
12352201
PubChem物質ID:
329799699
NACRES:
NA.25

生物源

bacterial (Corynebacterium)

品質等級

300

化驗

≥98%

形狀

amorphous powder

雜質

<0.05 mol % fructose 1,6-diphosphate
<1.5 mol % glucose 6-phosphate

顏色

white to off-white

溶解度

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

正離子痕跡

Na: 14.6-15.6% (dry basis)

應用

agriculture

儲存溫度

−20°C

SMILES 字串

O.[Na+].[Na+].OC[C@@]1(O)O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13;;;/h3-5,7-10H,1-2H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t3-,4-,5+,6-;;;/m1.../s1

InChI 密鑰

VSCMQICEHMPOEC-HTKRKRNRSA-L

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相关类别

應用

D-果糖-6-磷酸（F6P）是糖酵解途径的糖中间体，可用于帮助鉴定、区分和表征一些酶，例如磷酸果糖激酶、焦磷酸依赖性果糖-6-磷酸1-磷酸转移酶、D-果糖6-磷酸醛缩酶、谷氨酰胺：果糖-6-磷酸酰胺转移酶和葡糖胺6P合酶。

生化／生理作用

6-磷酸果糖是通过磷酸葡萄糖异构酶将6-磷酸葡萄糖异构化而产生的糖酵解中间体。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Yimin Qian et al.
Bioorganic & medicinal chemistry letters, 21(21), 6264-6269 (2011-10-01)
Through high throughput screening and subsequent hit identification and optimization, we synthesized a series of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as the first reported potent and reversible GFAT inhibitors. SAR studies of this class of compounds indicated significant impact on GFAT inhibition potency
Quan Wang et al.
Glycobiology, 22(12), 1760-1767 (2012-07-27)
Streptococcus pneumoniae is a major human pathogen associated with diseases worldwide. The capsular polysaccharides (CPSs) are considered a major virulence factor and are targets for a vaccine. d-Mannitol was found to be present in the CPS of several S. pneumoniae
Kay O Broschat et al.
The Journal of biological chemistry, 277(17), 14764-14770 (2002-02-14)
Glutamine-fructose-6-phosphate amidotransferase (GFAT) catalyzes the first committed step in the pathway for biosynthesis of hexosamines in mammals. A member of the N-terminal nucleophile class of amidotransferases, GFAT transfers the amino group from the L-glutamine amide to D-fructose 6-phosphate, producing glutamic
Wai Yee Phong et al.
PloS one, 8(2), e56037-e56037 (2013-02-15)
Metabolic versatility has been increasingly recognized as a major virulence mechanism that enables Mycobacterium tuberculosis to persist in many microenvironments encountered in its host. Glucose is one of the most abundant carbon sources that is exploited by many pathogenic bacteria
Philippe Durand et al.
Archives of biochemistry and biophysics, 474(2), 302-317 (2008-02-19)
L-Glutamine:d-fructose-6-phosphate amidotransferase, also known as glucosamine-6-phosphate synthase (GlcN6P synthase), which catalyzes the first step in a pathway leading to the formation of uridine 5'-diphospho-N-acetyl-d-glucosamine (UDP-GlcNAc), is a key point in the metabolic control of the biosynthesis of amino sugar-containing macromolecules.
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