D1822

多西环素 一水合物

• 别名: 6-Deoxy-5-oxytetracycline monohydrate, Doxycycline
• 经验公式（希尔记法）: C₂₂H₂₄N₂O₈ · H₂O
• CAS号: 17086-28-1
• 分子量: 462.45
• MDL號碼: MFCD02682958
• 分類程式碼代碼: 51284030
• PubChem物質ID: 329798712
• NACRES: NA.85

属性

• 形狀: powder or crystals
• 品質等級: 200
• 抗生素活性譜: Gram-negative bacteria; Gram-positive bacteria; mycoplasma; parasites
• 作用方式: protein synthesis | interferes
• 儲存溫度: −20°C
• SMILES 字串: O.C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14
• InChI: 1S/C22H24N2O8.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H2/t7-,10+,14+,15-,17-,22-;/m0./s1
• InChI 密鑰: XQTWDDCIUJNLTR-CVHRZJFOSA-N
• 基因資訊: human ... MMP1(4312) , MMP13(4322) , MMP7(4316) , MMP8(4317)

说明

應用

• In yeast cells, doxycycline has been used in doxycycline-inducible system for overexpression of methyltransferase Hmt1 (hnRNP methyltransferase 1).
• It has been used in the doxycycline-inducible IFITM (interferon-induced transmembrane) cell lines.
• It has also been used as an antimicrobial agent.

生化／生理作用

Doxycycline is a semisynthetic tetracycline that is active against bacteria, mycoplasma and protozoan parasites. It inhibits the bacterial protein synthesis by inhibiting the interaction of aminoacyl-tRNA and the bacterial ribosome.

其他說明

Keep container tightly closed in a dry and well-ventilated place.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 + P330 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable