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MMP7

matrix metallopeptidase 7 (matrilysin, uterine)

Synonyms:
MMP-7, MPSL1, PUMP-1
Species:
UniProtKB ID:
Gene ID:
  • Human(4316) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17393) matrix metallopeptidase 7
  • Rat(25335) matrix metallopeptidase 7
  • domestic guinea pig(100727130) matrix metallopeptidase 7 (matrilysin, uterine)
  • dog(489432) matrix metallopeptidase 7 (matrilysin, uterine)
  • chicken(418983) matrix metallopeptidase 7 (matrilysin, uterine)
  • naked mole-rat(101718114) matrix metallopeptidase 7 (matrilysin, uterine)
  • cow(286794) matrix metallopeptidase 7 (matrilysin, uterine)
  • sheep(100192317) matrix metallopeptidase 7 (matrilysin, uterine)

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ELISA

Product Number
Description
Species
Human MMP-7 ELISA Kit, on for cell culture supernatant,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
Anti-MMP7 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-MMP-7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-MMP7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-MMP-7 (Ab-1) Mouse mAb (141-7B2), liquid, clone 141-7B2, Calbiochem®,
Species Reactivity
human
Application

Small Molecule - Inhibitor

Product Number
Description
Species
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Doxycycline monohydrate, ,
Species
human
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse
CP-101537, ≥98% (HPLC),
Species
human, rat, mouse
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse

Proteins

Product Number
Description
Species
Matrix Metalloproteinase-7 human, ~0.1 mg/mL, recombinant, expressed in E. coli, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP7,
Species
human