C1244

CHM-1 hydrate

≥99% (HPLC), solid

• 别名: 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
• 经验公式（希尔记法）: C₁₆H₁₀FNO₃ · xH₂O
• CAS号: 154554-41-3
• 分子量: 283.25 (anhydrous basis)
• MDL號碼: MFCD11114577
• 分類程式碼代碼: 12352202
• PubChem物質ID: 329774746
• NACRES: NA.77

属性

• 化驗: ≥99% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• 溶解度: DMSO: ≥5 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: O.Fc1ccccc1C2=CC(=O)c3cc4OCOc4cc3N2
• InChI: 1S/C16H10FNO3.H2O/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12;/h1-7H,8H2,(H,18,19);1H2
• InChI 密鑰: KIAVGSCBJYDTIM-UHFFFAOYSA-N

说明

生化／生理作用

CHM-1 possess antimitotic,antiangiogenic and antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization.

特點和優勢

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)