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Merck

B3412

Sigma-Aldrich

小檗碱 半硫酸盐

≥95%

别名:

黄连素

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About This Item

线性分子式:
C20H18NO4 · 1/2SO4
CAS号:
分子量:
384.39
顏色索引編號:
75160
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.32

化驗

≥95%

形狀

powder

溶解度

methanol: soluble

SMILES 字串

[O-]S([O-])(=O)=O.COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.COc6ccc7cc8-c9cc%10OCOc%10cc9CC[n+]8cc7c6OC

InChI

1S/2C20H18NO4.H2O4S/c2*1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4/h2*3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4)/q2*+1;/p-2

InChI 密鑰

OJVABJMSSDUECT-UHFFFAOYSA-L

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應用

Fluorescent stain for heparin in mast cells

生化/生理作用

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Dong-Gu Kim et al.
Molecular medicine reports, 21(1), 258-266 (2019-11-21)
The major role of inner medullary collecting duct (IMCD) cells is to maintain water and sodium homeostasis. In addition to the major role, it also participates in the protection of renal and systemic inflammation. Although IMCD cells could take part

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Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.

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