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About This Item
经验公式（希尔记法）:
C8H9FN2O2S · HCl
CAS号:
分子量:
252.69
Beilstein:
9083148
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77
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化驗
≥97% (silver nitrate titration)
形狀
powder
mp
190-191 ºC
溶解度
H2O: 50 mM (Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems.)
儲存溫度
−20°C
SMILES 字串
Cl[H].NC(=N)c1ccc(CS(F)(=O)=O)cc1
InChI
1S/C8H9FN2O2S.ClH/c9-14(12,13)5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5H2,(H3,10,11);1H
InChI 密鑰
KHLLRHIUKOJXLL-UHFFFAOYSA-N
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一般說明
4-氨基苯甲磺酰氟盐酸盐相对无毒。
應用
4-氨基苯甲磺酰氟盐酸盐已用作：
- 抑制剂鸡尾酒的组分，用于全血收集和血浆分离
- 十二烷基硫酸钠（SDS）样品缓冲液的组分，用于制备全细胞提取物
- 胰蛋白酶抑制剂，用于测量其抑制效率，并确定量子点荧光共振能量转移（FRET）式酶探针的功效
生化／生理作用
4-氨基苯甲磺酰氟盐酸盐（p-APMSF）能抑制镰孢菌产生的胰蛋白酶样蛋白酶。它还能够阻断牛Xa因子、人纤溶酶和人补体蛋白酶C1r和C1s。
具有赖氨酸或精氨酸底物特异性的丝氨酸蛋白酶的不可逆抑制剂。有效浓度是10-100 μM。常用于表征新发现的蛋白酶。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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