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生物源
human
品質等級
重組細胞
expressed in baculovirus infected insect cells
化驗
≥95% (SDS-PAGE)
形狀
lyophilized powder
效力
1-10 ng/mL ED50
分子量
dimer 26 kDa (containing 116 amino acid residues βA subunits)
包裝
pkg of 10 μg
pkg of 5 μg
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
UniProt登錄號
儲存溫度
−20°C
基因資訊
human ... INHBA(3624)
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一般說明
带有两个外显子的激活素A基因位于人染色体2q35上。激活素A也称为抑制素α-亚基，属于蛋白质的TGF-β（转化生长因子β）超家族，其表达仅限于性腺、胎盘和肾上腺皮质。
應用
人激活素A已被用作 modified barth′s saline 的成分，用于体外诱导前肾。它还被用作罗斯威尔公园纪念研究所（RPMI）培养基的成分，用于在体外诱导多能真皮成纤维细胞的胰腺分化。
生化／生理作用
激活素在激素生成、细胞稳态和分化程序的调节中起着至关重要的作用。激活素A和B的表达升高会导致肌肉质量下降。激活素A和B都有望用作慢性疲劳综合征/肌痛性脑脊髓炎（CFS / ME）的血清标志物。
外觀
0.2μ 冻干10 mM 柠檬酸钠 (pH 3.0) 滤过溶液。
分析報告
其生物活性由其抑制小鼠 MPC-11 细胞增殖的能力决定。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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