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Merck

A3673

Sigma-Aldrich

抗-小鼠IgG(γ-链特异性)−过氧化物酶 山羊抗

affinity isolated antibody, buffered aqueous solution

别名:

Goat Anti-Mouse IgG (γ-chain specific)−HRP

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

goat

品質等級

共軛

peroxidase conjugate

抗體表格

affinity isolated antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse

技術

direct ELISA: 1:15,000

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

一般說明

免疫球蛋白G(IgG)是一种糖蛋白抗体,其可调节免疫反应,如吞噬作用,也可参与自身免疫疾病的发展。小鼠IgG具有四种不同的同种型,即IgG1、IgG2a、IgG2b和IgG3。IgG1可调节小鼠的补体结合。
当针对纯化的小鼠IgA、IgG和IgM骨髓瘤蛋白进行测试时,山羊抗小鼠IgG(γ-链特异性)-过氧化物酶抗体对小鼠IgG具有特异性。

免疫原

纯化小鼠IgG

應用

HRP偶联的山羊抗小鼠γ链特异性用于通过ELISA检测血清和粘膜洗液中针对HIV1的中和抗体。3′3′5,5 四甲基联苯胺(Sigma)可用作开发底物。
山羊抗小鼠IgG(γ-链特异性)过氧化物酶抗体可用于ELISA应用,稀释度为1:3000。

外觀

0.01 M磷酸盐缓冲液,pH 7.4,含有1%牛血清白蛋白和防腐剂。

準備報告

采用Wilson,M.B.和Nakane,P.K.在《免疫荧光及相关染色技术》中描述的过碘酸盐法制备(Elsevier/North Holland Biomedical Press,Amsterdam,p215 (1978))。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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象形圖

Exclamation markEnvironment

訊號詞

Warning

危險分類

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Basil Rapoport et al.
Journal of immunology (Baltimore, Md. : 1950), 197(12), 4560-4568 (2016-12-04)
Graves' hyperthyroidism, a common autoimmune disease caused by pathogenic autoantibodies to the thyrotropin (TSH) receptor (TSHR), can be treated but not cured. This single autoantigenic target makes Graves' disease a prime candidate for Ag-specific immunotherapy. Previously, in an induced mouse
Ashwini S Phadnis-Moghe et al.
Toxicology and applied pharmacology, 310, 41-50 (2016-08-23)
The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is a strong AHR agonist, causes significant suppression of human B cell activation and differentiation. The current studies describe the identification of Src homology phosphatase 1 (SHP-1) encoded by the gene PTPN6 as a
Kjersti Daae Horvei et al.
PloS one, 12(11), e0188863-e0188863 (2017-12-01)
FcγRIIB-/-yaa mice develop severe lupus glomerulonephritis due to lack of an inhibitory immune cell receptor combined with a Y-chromosome linked autoimmune accelerator mutation. In the present study, we have investigated nephritis development and progression in FcγRIIB-/-yaa mice to find shared
Yuji Nagayama et al.
Journal of immunology (Baltimore, Md. : 1950), 170(7), 3522-3527 (2003-03-21)
Graves' hyperthyroidism has long been considered to be a Th2-type autoimmune disease because it is directly mediated by autoantibodies against the thyrotropin receptor (TSHR). However, several lines of evidence have recently challenged this concept. The present study evaluated the Th1/Th2
Alana M Thackray et al.
The Biochemical journal, 400(2), 349-358 (2006-08-03)
Ovine PBMCs (peripheral blood mononuclear cells) express PrP(C) [cellular PrP (prion-related protein)] and have the potential to harbour and release disease-associated forms of PrP during scrapie in sheep. Cell-surface PrP(C) expression by PBMCs, together with plasma PrP(C) levels, may contribute

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