推荐产品
产品名称
DL-2-氨基己二酸, ≥99%
方案
≥99%
表单
powder
mp
196-198 °C (lit.)
储存温度
2-8°C
SMILES字符串
NC(CCCC(O)=O)C(O)=O
InChI
1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)
InChI key
OYIFNHCXNCRBQI-UHFFFAOYSA-N
基因信息
rat ... Grin2b(24410)
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应用
DL-2-氨基己二酸(AAA)已被用作一种astrotoxin 毒素,用于杀死可阻止移植的细胞有效整合到视网膜中的星形胶质细胞。它还被用作胶质毒素来研究星形胶质细胞膨胀对弯曲度的影响。
生化/生理作用
DL-2-氨基己二酸(AAA)是谷氨酸盐的六碳同系物和胶质毒性化合物。它通常用于显著减少小脑培养物中的星形胶质细胞数目,该培养物可用作研究a-氨基己二酸诱导的神经胶质毒性机制的模型。
警示用语:
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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H Bräuner-Osborne et al.
Journal of medicinal chemistry, 39(16), 3188-3194 (1996-08-02)
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