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product name
丙氨酸-谷氨酰胺, ≥98% (HPLC)
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to off-white
SMILES 字串
NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
InChI
1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
InChI 密鑰
HJCMDXDYPOUFDY-WHFBIAKZSA-N
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應用
L-谷氨酰胺是细胞培养的一种必需补充剂。游离氨基酸 L-谷氨酰胺不稳定,通常会降解成焦谷氨酸。丙氨酰-L-谷氨酰胺(Ala-Gln)和 Gylcyl-L-谷氨酰胺(Gly-Gln)用作细胞培养中,作为稳定化 L-谷氨酰胺的替代运输形式。使用 L-丙氨酰谷氨酰胺代替 L-谷氨酰胺的主要优点是它降低了细胞培养过程中产生的氨水平。
生化/生理作用
丙氨酰谷氨酰胺是一种在生物制药生产中广泛使用的 L-谷氨酰胺的替代补充剂。丙氨酰谷氨酰胺还可作为抗氧化剂(过氧化物)和抗凋亡(LPS 诱导)因子。Ala-Gln 已被用于研究损伤和败血症,以及研究辐射对体内亮氨酸和蛋白质代谢的影响。 Ala-Gln 已被用于研究体外多形核白细胞和髓过氧化物酶活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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