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Merck
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文件

SMB00962

Sigma-Aldrich

Phenylacetyl-L-glutamine

≥95%

别名:

(S)-5-Amino-5-oxo-2-(2-phenylacetamido)pentanoic acid, N-Phenylacetylglutamine, Phenylacetylglutamine

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About This Item

经验公式（希尔记法）:
C13H16N2O4
CAS号:
28047-15-6
分子量:
264.28
MDL號碼:
MFCD01725188
分類程式碼代碼:
12352209
NACRES:
NA.26

生物源

synthetic

品質等級

100

等級

research grade

化驗

≥95%

形狀

powder

儲存條件

(Store in tight containers in a cool and dry place)

技術

HPLC: suitable

顏色

off-white

正離子痕跡

C: 56.1—62%

儲存溫度

room temp

InChI

1S/C13H16N2O4/c14-11(16)7-6-10(13(18)19)15-12(17)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,14,16)(H,15,17)(H,18,19)/t10-/m0/s1

InChI 密鑰

JFLIEFSWGNOPJJ-JTQLQIEISA-N

一般說明

Phenylacetyl-L-glutamine is a primary human metabolite formed from phenylacetate in presence of glutamine in the liver. It is also considered as a gut-microbiome derived uremic toxin. Phenylacetyl-L-glutamine urine levels serve as an effective biomarker for the excretion of nitrogenous waste. Also, peripheral artery disease patients exhibit higher circulating concentration of phenylacetyl-L-glutamine, and high plasma phenylacetyl-L-glutamine levels are associated with cardiovascular disease.

應用

Phenylacetyl-ʟ-glutamine is a versatile compound that finds application in microbiome and metabolomics research.

特點和優勢

  • Ideal for biochemical, microbiome and metabolomics studies
  • High quality product for research applications

其他說明

For additional information on our range of Biochemicals, please complete this form.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
MKCW0986
MKCS8960
MKCQ8148
MKCN6319

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Sandi M Azab et al.
Journal of clinical medicine, 9(6) (2020-06-21)
Peripheral artery disease (PAD) is characterized by the atherosclerotic narrowing of lower limb vessels, leading to ischemic muscle pain in older persons. Some patients experience progression to advanced chronic limb-threatening ischemia (CLTI) with poor long-term survivorship. Herein, we performed serum
Lu Dai et al.
Toxins, 12(6) (2020-05-31)
Gut microbial metabolism is not only an important source of uremic toxins but may also help to maintain the vitamin K stores of the host. We hypothesized that sevelamer therapy, a commonly used phosphate binder in patients with end-stage kidney
Ina Nemet et al.
Cell, 180(5), 862-877 (2020-03-07)
Using untargeted metabolomics (n = 1,162 subjects), the plasma metabolite (m/z = 265.1188) phenylacetylglutamine (PAGln) was discovered and then shown in an independent cohort (n = 4,000 subjects) to be associated with cardiovascular disease (CVD) and incident major adverse cardiovascular events (myocardial infarction

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