1.07730

硅胶60 GF254

for thin-layer chromatography

• 别名: 硅胶
• CAS号: 112926-00-8
• MDL號碼: MFCD00011232
• 分類程式碼代碼: 41115711
• 酶委員會索引編號: 231-545-4
• NACRES: NB.21

属性

• 材料: silica gel 60 matrix
• 品質等級: 100
• 形狀: powder
• 效力: >5000 mg/kg LD₅₀, skin (Rabbit)
• 特點: binder Gypsum; fluorescent indicator
• 包裝: pkg of 25 kg
• 技術: thin layer chromatography (TLC): suitable
• 粒徑: 5-40 μm
• 孔徑: 60 Å medium pore diameter
• pH值: 7 (20 °C, 100 g/L in H₂O, slurry)
• bp: 2230 °C
• mp: >1600 °C
• 體積密度: 200‑800 kg/m³
• 儲存溫度: no temp limit
• SMILES 字串: O=[Si]=O
• InChI: 1S/O2Si/c1-3-2
• InChI 密鑰: VYPSYNLAJGMNEJ-UHFFFAOYSA-N

说明

一般說明

标准化的吸附剂确保每一次结果的可靠性。我们广泛的产品谱可满足各种不同的需求。在TLC中，硅胶60吸附剂被认为是最通用的吸附剂。我们的硅胶60产品分若干等级，其颗粒大小介于5-40 µm范围内：带石膏粘结剂硅，不带粘结剂硅和带荧光指示剂的硅。我们还提供高品质的氧化铝、微晶纤维素和硅藻石（也称为硅藻土）。

應用

• Chromatographic Separation of the Novel Hypoglycemic Drug Mitiglinide in its Bulk Powder and Pharmaceutical Formulation: Forced Degradation and Validated Stability-Indicating HPTLC/Densitometry and HPLC/UV Methods.: This research demonstrates the use of Silica gel 60 GF254 in the chromatographic separation of Mitiglinide, providing robust methods for stability and degradation analysis crucial for regulatory compliance and quality assurance in pharmaceuticals (Eissa MS et al., 2020).


• Quality Risk Management-Based AQbD Approach to Development of VEER Chromatography Method for the Estimation of Multiple Combined Formulations of Anti-Hypertensive Drugs.: Leveraging Silica gel 60 GF254, this study outlines a novel chromatographic method development under the Analytical Quality by Design (AQbD) framework, enhancing the reliability and efficiency of drug analysis processes (Prajapati PB et al., 2021).


• HPTLC and Spectrophotometric Estimation of Febuxostat and Diclofenac Potassium in Their Combined Tablets.: Utilizing Silica gel 60 GF254, this study presents a high-performance thin-layer chromatographic method for simultaneous estimation of Febuxostat and Diclofenac, demonstrating the gels utility in multi-drug analysis (El-Yazbi FA et al., 2016).


• Distribution of withaferin A, an anticancer potential agent, in different parts of two varieties of Withania somnifera (L.) Dunal. grown in Sri Lanka.: This research used Silica gel 60 GF254 in the quantification of withaferin A across different plant parts, highlighting its application in the study of pharmacologically active compounds in medicinal plants (Siriwardane AS et al., 2013).


• Simultaneous determination of metronidazole and miconazole nitrate in gel by HPTLC.: Demonstrating the adaptability of Silica gel 60 GF254, this study provides a validated HPTLC method for analyzing metronidazole and miconazole nitrate in a topical gel, crucial for ensuring therapeutic efficacy and safety in dermatological treatments (Meshram DB et al., 2009).

分析報告

pH-值（10%混悬液）：6.0 - 7.0
Fe（铁）： ≤ 0.02%
硫酸钙（CaSO₄·0.5 H₂O）：12.0 - 13.5%
粒度：90% <55 µm
应用测试：符合
紫外吸收（二氯甲烷提取物）：符合
粒度数据与添加添加剂前的纯硅胶有关。

安全信息

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable