推荐产品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (791637C-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
1 mg/mL (791637C-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) is a deuterated phospholipid. The lipid comprises phosphatidylcholine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phospholipids, in general are amphiphilic and have phosphocholine moiety attached to sn-3 position of glycerol. Phosphatidylcholine is a glycerophospholipid and is a cell membrane component.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
應用
15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) has been used:
- as a component of extraction solvent for lipid isolation from biological samples
- as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)
- as an internal standard in analysis of lipids from cystic fibrosis derived cell lines
生化／生理作用
Phosphatidylcholine (PC) levels are crucial for mediating various cellular processes including membrane movement and cell differentiation. A disturbance in PC levels is implicated in various metabolic disorders.
包裝
2 mL Amber Glass Sealed Ampule (791637C-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
产品编号
说明
价格
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
does not flash
閃點（°C）
does not flash
V Craige Trenerry et al.
Food chemistry, 141(2), 1451-1460 (2013-06-26)
Milk polar lipids are an important class of biologically active species for human health and for improving the physical functionality of food ingredients. Milk polar lipids from 144 multiparous Holstein-Friesian dairy cows fed different diets were analysed using ultra-high-performance liquid
Alessandra Mingione et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 54(1), 110-125 (2020-01-31)
Cystic Fibrosis (CF) is an inherited disease associated with a variety of mutations affecting the CFTR gene. A deletion of phenylalanine 508 (F508) affects more than 70% of patients and results in unfolded proteins accumulation, originating a proteinopathy responsible for
Bjoern Titz et al.
Computational and structural biotechnology journal, 18, 1056-1073 (2020-05-19)
Cigarette smoke (CS) causes adverse health effects and, for smoker who do not quit, modified risk tobacco products (MRTPs) can be an alternative to reduce the risk of developing smoking-related diseases. Standard toxicological endpoints can lack sensitivity, with systems toxicology
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
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