推荐产品
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mL (791643C-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
浓度
1 mg/mL (791643C-1mg)
运输
dry ice
储存温度
−20°C
一般描述
18:1-d7 Lyso PC 1油酰基(d7)-2-羟基-sn-甘油-3-磷酸胆碱是氘代磷脂。该脂质溶血磷脂酰胆碱是以油酸酯化。油酸包含氘离子。溶血磷脂酰胆碱（LPC） 是在磷脂酶 A2 的作用下由磷脂酰胆碱衍生而来。
这种氘标记的脂质也可用于多种脂质标准品制剂中。SPLASH™ LIPIDOMIX™ 标准品包括与人血浆的所有主要脂质类别对应的脂质，从而实现一种简单的内标溶液适用每种样品。
应用
18:1-d7 Lyso PC 已用于:
- 作为高效液相色谱电喷雾电离串联质谱（HPLC-ESIMS/MS） 的内标物，用于来源于骨髓的巨噬细胞的脂质组学分析
- 作为提取溶剂的成分，用于从生物样品中分离脂质
- 作为液相色谱串联质谱（LC-MS/MS）中血清样品的内标物
生化/生理作用
溶血磷脂酰胆碱（LPC）。LPC 水平升高与糖尿病和心血管疾病有关。LPC 刺激细胞因子并与过敏性疾病有关。它还导致膜上的裂解。
包装
5 mL透明玻璃密封安瓿（791643C-1mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
Shi-Hui Law et al.
International journal of molecular sciences, 20(5) (2019-03-09)
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively associated with cardiovascular and neurodegenerative diseases. However, findings from recent clinical lipidomic studies of LPC have been controversial. A key issue is the complexity of the enzymatic cascade involved in
Preeti Bansal et al.
Scientific reports, 6, 27430-27430 (2016-06-11)
Phospholipase A2 (sPLA2), pivotal for allergic and inflammatory response, hydrolyses phosphatidylcholine (PC) to lysophosphatidylcholine (LPC). In present study, the role of LPC in allergic airway disease manifestation was studied using mouse model. Balb/c mice were immunized using cockroach extract (CE)
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持