907197

1,4-Dinitro-1-imidazole

• 别名: 1,4-DNIm, 1,4-Dinitroimidazole, Bifunctional bioconjugation reagent
• 经验公式（希尔记法）: C₃H₂N₄O₄
• CAS号: 19182-81-1
• 分子量: 158.07
• MDL编号: MFCD00297235
• UNSPSC代码: 12352005

属性

• 方案: ≥95%
• 表单: solid
• 储存温度: −20°C
• InChI: 1S/C3H2N4O4/c8-6(9)3-1-5(2-4-3)7(10)11/h1-2H
• InChI key: HZPSREFSUPXCMN-UHFFFAOYSA-N

说明

应用

1,4-Dinitro-1-imidazole (1,4-DNIm) and other dinitroimidazoles were demonstrated to be bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. In acidic to neutral aqueous conditions, 1,4-DNIms chemoselectively react with cysteines; in organic solvents in the presence of base, 1,4-DNIms chemoselectively react with lysines to form stable conjugates

其他说明

Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H302
• 预防措施声明: P264 - P270 - P301 + P312 - P501
• 危险分类: Acute Tox. 4 Oral
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable