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Merck

182028

Sigma-Aldrich

聚环氧乙烷

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

别名:

PEO

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About This Item

线性分子式:
(-CH2CH2O-)n
CAS号:
MDL號碼:
分類程式碼代碼:
12352104
PubChem物質ID:
NACRES:
NA.23

product name

聚环氧乙烷, average Mv 600,000 (nominal), powder

形狀

powder

品質等級

分子量

average Mv 600,000 (nominal)

包含

200-500 ppm BHT as inhibitor

黏度

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

轉變溫度

Tm 65 °C

Ω-end

hydroxyl

α-end

hydroxyl

應用

battery manufacturing

SMILES 字串

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般說明

聚环氧乙烷(PEO)2是一种高分子量、非离子水溶性聚合物。它在水化时形成凝胶,并具有良好的膨胀能力。EPO聚合物无毒,广泛用于药物递送系统以改善药物可溶性。

應用

聚环氧乙烷可用于制备:
  • 用于药物缓释的可生物吸收、可注射水凝胶。
  • 用于燃料电池的PEO/氧化石墨烯复合电极膜。
  • 聚环氧乙烷-b-聚ε-己内酯(PEO-b-PC)二嵌段共聚物。内含氯沙坦钾的(PEO-b-PCL)共聚物可用作药物载体。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jun Li et al.
Journal of biomedical materials research. Part A, 65(2), 196-202 (2003-05-08)
Polymeric hydrogels long have attracted interest for biomaterials applications because of their generally favorable biocompatibility. High in water content, they are particularly attractive for delivery of delicate bioactive agents, such as proteins. However, because they require covalent crosslinking for gelation
Angeliki Chroni et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-24)
We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers were prepared by organic solvent evaporation method
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a

商品

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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