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Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

别名:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
物种:
UniProtKB ID:
基因ID:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

货号
说明
物种
丁螺环酮盐酸盐 盐酸盐, ,
物种
human
(R)-(+)-8-Hydroxy-DPAT hydrobromide, ≥98% (HPLC), solid,
物种
human
丁螺环酮盐酸盐 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
盐酸丁螺环酮, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
1-(3-氯苯基)哌嗪 盐酸盐, 99%,
物种
rat
WAY-100635 马来酸盐, powder,
物种
human
1-(3-甲氧基苯基)哌嗪, 95%,
物种
rat
GR 103691, ≥98% (HPLC), solid,
物种
rat
1-(4-甲氧基苯基)哌嗪, 97%,
物种
mouse, rat

Antibodies

货号
说明
物种反应性
应用
抗-血清素 兔抗, whole antiserum,
物种反应性
human, rat
应用
immunohistochemistry
抗-5-羟色胺抗体,克隆YC5/45, culture supernatant, clone YC5/45, Chemicon®,
物种反应性
human, lizard, mouse, pig, rabbit, rat
应用
immunohistochemistry
血清素受体1A抗体, serum, Chemicon®,
物种反应性
rat
应用
immunohistochemistry
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Anti-HTR1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
(S)-(-)-普奈洛尔 盐酸盐, ≥98% (TLC), powder,
物种
human
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
维拉佐酮 盐酸盐, ≥98% (HPLC),
物种
human
维拉佐酮 盐酸盐 溶液, 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®,
物种
human
1,2,3,4-四氢异喹啉, 95%,
物种
rat, human
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
BP897, >98% (HPLC), solid,
物种
human, rat
米非司酮, ≥98%,
物种
human, mouse, rat
氟哌啶醇, powder,
物种
human, rat
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human HTR1A,
物种
human