F6300

Flumazenil

>99% (HPLC), solid, benzodiazepine receptor antagonist

• Synonyme(s) : Ro 15-1788, Ro15-1788
• Formule empirique (notation de Hill): C₁₅H₁₄FN₃O₃
• Numéro CAS: 78755-81-4
• Poids moléculaire : 303.29
• Numéro MDL: MFCD00242764
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278437
• Nomenclature NACRES : NA.77

Propriétés

• product name: Flumazenil, >99% (HPLC), solid
• Niveau de qualité: 100
• Pureté: >99% (HPLC)
• Forme: solid
• Couleur: white
• Auteur: Roche
• Température de stockage: 2-8°C
• Chaîne SMILES: CCOC(=O)c1ncn-2c1CN(C)C(=O)c3cc(F)ccc-23
• InChI: 1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
• Clé InChI: OFBIFZUFASYYRE-UHFFFAOYSA-N
• Informations sur le gène: human ... BZRAP1(9256) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) ; rat ... Gabra2(29706) , Gabrg1(140674)

Description

Description générale

Flumazenil reverses sedative and hypnotic effects of benzodiazepines. It is used to increase acquisition, enhance retention and treat amnesia in mice.

Actions biochimiques/physiologiques

Highly specific benzodiazepine receptor antagonist.

Caractéristiques et avantages

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)