SRE0069

Phosphoglucomutase from rabbit muscle

• Sinónimos: α-D-Glucose-1,6-bisphosphatase, α-D-Glucose-1-phosphate phosphotransferase
• Número de CAS: 9001-81-4
• Comisión internacional de enzimas: 5.4.2.2 (BRENDA, IUBMB)
• Número MDL: MFCD00131886
• Código UNSPSC: 12352204
• NACRES: NA.32

Propiedades

• Formulario: lyophilized powder
• Nivel de calidad: 200
• actividad específica: ≥100 units/mg protein
• actividad extraña: Lactic dehydroenase ≤0.5%; Phosphoglucose Isomerase ≤0.01%; pyruvate kinase ≤0.05%
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Research area: CellSignalling. The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with a unique four-domain architecture.[1]

Aplicación

Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase.[1]

Acciones bioquímicas o fisiológicas

Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis.[1]

Definición de unidad

One unit will convert 1.0 μmole of α-D-glucose 1-phosphate to α-D-glucose 6-phosphate per min at pH 7.4 at 30 °C.

Forma física

Lyophilized powder containing Tris HCl, EDTA, magnesium acetate and carbohydrate

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable