SML3687

TL8-506

≥98% (HPLC)

• Sinónimos: (1E,4E)-Ethyl 2-amino-8-(3-cyanophenyl)-3H-1-benzo[b]azepine-4-carboxylate, Ethyl 2-amino-8-(3-cyanophenyl)-3H-1-benzazepine-4-carboxylate, TL 8-506, TLR 8-506
• Fórmula empírica (notación de Hill): C₂₀H₁₇N₃O₂
• Número CAS: 1268163-15-0
• Peso molecular: 331.37
• UNSPSC Code: 12352200
• MDL number: MFCD28359121
• NACRES: NA.21
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• storage temp.: -10 to -25°C

Descripción

Biochem/physiol Actions

Motolimod (VTX-2337) analog and a toll-like receptor 8 (TLR8)-selective agonist with stronger activity than resiquimod (R848) and CL075 (3M002).

TL8-506 is a motolimod (VTX-2337) analog and a benzoazepine class toll-like receptor 8 (TLR8)-selective agonist. TL8-506 is commonly employed in the concentration range from 0.1 μg/mL to 1 μg/mL for stimulating cell surface TLR8 in cultures and is reported to be a stronger TLR8 ligand than the imidazoquinoline (IMDQ) derivatives (IQDs) resiquimod (R848) and CL075 (3M002).

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable